Negative chronotropic effects of McN A-343 and nicotine in isolated guinea-pig atria: insensitivity to blockade by tetrodotoxin.
نویسندگان
چکیده
ERNAU 25 Interference with Excitation by 5-Benzoyloxy-2-Iminohexahydropyrimidine Hydrochloride. M. Y. SPIEGELSTEIN AND C. Y. KAO 34 Negative Chronotropic Effects of McN A-343 and Nicotine in Isolated Guinea-Pig Atria: Insensitivity to Blockade by Tetrodotoxin. ACHILLES J. PAPPANO AND ROBERT A. REMBISH 40 Ganglionic Stimulation: Mechanism of the Positive Inotropic and Chronotropic Effects of Angiotensin. WILUAU C. FARE AND GUNTER GRUPP 48 The Relative Effect of the Renal Pressor and Sympathetic Nervous Systems on Vascular Capacity during Hypotension. D. W. DUCHARME AND L. BECK 56 Direct and Systemic Effects of Guanethidine on Renal Function. RONALD L.
منابع مشابه
The pathophysiology of barium: hypokalemic and cardiovascular effects.
ERNAU 25 Interference with Excitation by 5-Benzoyloxy-2-Iminohexahydropyrimidine Hydrochloride. M. Y. SPIEGELSTEIN AND C. Y. KAO 34 Negative Chronotropic Effects of McN A-343 and Nicotine in Isolated Guinea-Pig Atria: Insensitivity to Blockade by Tetrodotoxin. ACHILLES J. PAPPANO AND ROBERT A. REMBISH 40 Ganglionic Stimulation: Mechanism of the Positive Inotropic and Chronotropic Effects of Ang...
متن کاملThe relation between monoamines in brain and the anticonvulsant action of inhibition of carbonic anhydrase.
ERNAU 25 Interference with Excitation by 5-Benzoyloxy-2-Iminohexahydropyrimidine Hydrochloride. M. Y. SPIEGELSTEIN AND C. Y. KAO 34 Negative Chronotropic Effects of McN A-343 and Nicotine in Isolated Guinea-Pig Atria: Insensitivity to Blockade by Tetrodotoxin. ACHILLES J. PAPPANO AND ROBERT A. REMBISH 40 Ganglionic Stimulation: Mechanism of the Positive Inotropic and Chronotropic Effects of Ang...
متن کاملEffect of Sodium Valproate on Ouabain-Induced Arrhythmia in Isolated Guinea-Pig Atria
Sodium valproate (SV), an antiepileptic drug has several mechanism of action. It inhibits voltage sensitive Na+ channels and reduces intracellular Na accumulation. These actions are similar to that of both phenytoin and carbamazepine. We have investigated the direct cardiac action of SV and its effects on ouabain-induced arrhythmia in isolated guinea-pig atria. The guinea-pig atrium was dissect...
متن کاملاثرات قلبی- عروقی نوسکاپین، آلکالوئید ضد سرفه تریاک
Background: Noscapine is a phtalideisoquinoline alkaloid with known anti-tussive properties. Recently, some other pharmacological effects and new potential clinical applications have been proposed for the drug. Since there is no data regarding its cardiovascular effects, cardiovascular actions of Noscapine were investigated in the present study. Methods: In this experimental study,�the effe...
متن کاملEffect of imipramine and desipramine on adenosine receptors in isolated rat atria
The effect of different doses (1-50 µ M) of imipramine (IMI) and desipramine (DES) on the rate and force of contraction of isolated rat atria was studied. IMI and DES produced a dose-dependent increase in force of contraction (31- 94% for IMI and 35-118% for DES). Pretreatment of rats with reserpine (5 mg/kg) on the isolated atria with propranolol (1 µ g) inhibited the positive ionotropic eff...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of pharmacology and experimental therapeutics
دوره 177 1 شماره
صفحات -
تاریخ انتشار 1971